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Article

Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish.

Development (Cambridge, England) - 20 Jan 2021

Redl Stefan, de Jesus Domingues Antonio M, Caspani Edoardo, Möckel Stefanie, Salvenmoser Willi, Mendez-Lago Maria, Ketting René F

Abstract excerpt

Primordial germ cells (PGCs) are the precursors of germ cells, which migrate to the genital ridge during early development. Relatively little is known about PGCs after their migration. We studied this post-migratory stage using microscopy and sequencing techniques, and found that many PGC-specific genes, including genes known to induce PGC fate in the mouse, are only activated several days after migration. At...

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Identifiers

PMID: 33298460
DOI: 10.1242/dev.193060
PMCID: PMC7847270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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