Article

Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants

2024-08-30

Abstract excerpt

<h4>ABSTRACT</h4> Mammalian primordial germ cells (PGCs) migrate asynchronously through the embryonic hindgut and dorsal mesentery to reach the gonads. We previously found that interaction with different somatic niches regulates PGC proliferation along the migration route. To characterize transcriptional heterogeneity of migrating PGCs and their niches, we performed single-cell RNA sequencing of 13,262 mouse PGCs...

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Literature Corpus work: ef26f69c-fc31-5244-a0f5-830a268de4a8
DOI: 10.1101/2024.08.29.610420

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Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrantsDOI 10.1101/2024.08.29.610420Read

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