Article

Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells

2020-01-14

Abstract excerpt

<h4>SUMMARY</h4> In many animal models, primordial germ cell (PGC) development depends on maternally-deposited germ plasm to avoid somatic cell fate. Here, we show that PGCs respond to regulatory information from the germ plasm in two distinct phases and mechanisms in zebrafish. We show that PGCs commence zygotic genome activation together with the rest of the embryo with no demonstrable differences in transcript...

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Literature Corpus work: 68885da9-5674-5188-855d-631e86101797
DOI: 10.1101/2020.01.12.903336

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