Article

Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells

2024-02-21

Abstract excerpt

Accurate specification of female and male germ cells during embryonic development is critical for sexual reproduction. Primordial germ cells (PGCs) are the bipotential precursors of mature gametes that commit to an oogenic or spermatogenic fate in response to sex-determining cues from the fetal gonad. The critical processes required for PGCs to integrate and respond to signals from the somatic environment in gonad...

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Literature Corpus work: 1a5530fb-2dc3-5b33-b151-a7c03ddb4736
DOI: 10.1101/2024.02.19.581036

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