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Article

Autozygosity mapping and time-to-spontaneous delivery in Norwegian parent-offspring trios.

Human molecular genetics - 4 Feb 2021

Sole-Navais Pol, Bacelis Jonas, Helgeland Øyvind, Modzelewska Dominika, Vaudel Marc, Flatley Christopher, Andreassen Ole, Njølstad Pål R, Muglia Louis J, Johansson Stefan, Zhang Ge, Jacobsson Bo

Abstract excerpt

Parental genetic relatedness may lead to adverse health and fitness outcomes in the offspring. However, the degree to which it affects human delivery timing is unknown. We use genotype data from ≃25 000 parent-offspring trios from the Norwegian Mother, Father and Child Cohort Study to optimize runs of homozygosity (ROH) calling by maximizing the correlation between parental genetic relatedness and offspring ROHs....

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Identifiers

PMID: 33291140
DOI: 10.1093/hmg/ddaa255
PMCID: PMC7861013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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