Article
Clinicopathological features of mismatch repair protein expression patterns in colorectal cancer.
Pathology, research and practice - 1 Jan 2021
Lee Chung-Ta, Chow Nan-Haw, Chen Yi-Lin, Ho Chung-Liang, Yeh Yu-Min, Lin Shao-Chieh, Lin Peng-Chan, Lin Bo-Wen, Chu Chien-An, Tsai Hung-Wen, Lee Jenq-Chang
Abstract excerpt
Microsatellite instability (MSI) is reflective of a deficient mismatch repair (dMMR) system, which is mostly associated with the methylation of mismatch repair (MMR) genes and BRAF mutations in sporadic colorectal cancers (CRCs). We performed a retrospective study to analyze the clinicopathological features of dMMR CRCs and their association with the BRAF V600E mutation. The incidence of dMMR CRCs in our cohort...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
