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Prediction of biological behavior and prognosis of colorectal cancer patients by tumor MSI/MMR in the Chinese population

1 Dec 2016

Abstract excerpt

Abstract: Colorectal cancers (CRCs) exhibiting microsatellite instability (MSI) have special biological behavior. The clinical predictors for MSI and its survival relevance for the Chinese population were still unclear. Seven hundred ninety-five CRC patients were retrospectively assessed. Mismatch repair (MMR) proteins (MSH2, MSH6, PMS1, and MLH1) expression was detected by immunohistochemistry using tumor...

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PMID: 27994472
DOI: 10.2147/ott.s117089

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