Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of MED12 mutations in mesenchymal components of uterine adenomyomas.

Human pathology - 1 Mar 2021

Kito Masahiko, Maeda Daichi, Kudo-Asabe Yukitsugu, Tamura Daisuke, Makino Kenichi, Sageshima Masato, Nanjo Hiroshi, Terada Yukihiro, Goto Akiteru

Abstract excerpt

Adenomyoma of the uterus is a biphasic nodular lesion composed of a mesenchymal component with smooth muscle differentiation and a glandular epithelium. The neoplastic nature of uterine adenomyomas has been controversial because some are considered to be nodular adenomyosis. MED12 mutations are involved in the pathogenesis of uterine smooth muscle tumors (leiomyomas and leiomyosarcomas) and biphasic tumors of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Leiomyoma

Share to Mediator Complex

Share to Mutation

Share to Uterine Neoplasms

Source

Identifiers

PMID: 33259844
DOI: 10.1016/j.humpath.2020.11.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of MED12 mutations in mesenchymal components of uterine adenomyomas.PMID 33259844Read ↗

Comprehensive screening for MED12 mutations in gynaecological mesenchymal tumours identified morphologically distinctive mixed epithelial and stromal tumours.Semantic proximity Read ↗

MED12 alterations in both human benign and malignant uterine soft tissue tumors.Semantic proximity Read ↗

MED12 is frequently mutated in ovarian and other adnexal leiomyomas.Semantic proximity Read ↗

MED12 exon 2 mutations in uterine and extrauterine smooth muscle tumors.Semantic proximity Read ↗

Analysis of MED12 Mutation in Multiple Uterine Leiomyomas in South Korean patients.Semantic proximity Read ↗

Uterine adenosarcomas are mesenchymal neoplasms.Semantic proximity Read ↗

Whole exome sequencing in a random sample of North American women with leiomyomas identifies MED12 mutations in majority of uterine leiomyomas.Semantic proximity Read ↗

Prevalence of MED12 mutations in uterine and extrauterine smooth muscle tumours.Semantic proximity Read ↗

Detection of exon2-MED12 mutations in uterine leiomyomas from Syrian patients.Semantic proximity Read ↗

Distribution of MED12 mutations in fibroadenomas and phyllodes tumors of the breast--implications for tumor biology and pathological diagnosis.Semantic proximity Read ↗

MED12 exon 2 mutations in phyllodes tumors of the breast.Semantic proximity Read ↗

MED12 mutations in leiomyosarcoma and extrauterine leiomyoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.