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Article

Comprehensive screening for MED12 mutations in gynaecological mesenchymal tumours identified morphologically distinctive mixed epithelial and stromal tumours.

Histopathology - 1 May 2017

Yuan Chang-Tsu, Huang Wen-Chih, Lee Cheng-Han, Lin Ming-Chieh, Lee Chen-Hui, Kao Yu-Chien, Huang Hsuan-Ying, Kuo Kuan-Ting, Lee Jen-Chieh

Abstract excerpt

AIMS: MED12 exon 2 mutations have been identified in most uterine leiomyomas and mammary fibroepithelial tumours. MED12 has not been genotyped in most other gynaecological mesenchymal tumours. The purpose of this study was to determine the prevalence of MED12 mutations in uncommon gynaecological mesenchymal tumours. METHODS AND RESULTS: Sixty-eight uncommon gynaecological mesenchymal tumours were genotyped for...

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Source

Identifiers

PMID: 28002623
DOI: 10.1111/his.13156

Genes

MED12
JAZF1
PHF1
CDK4
MDM2
YWHAE
SUZ12

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Comprehensive screening for MED12 mutations in gynaecological mesenchymal tumours identified morphologically distinctive mixed epithelial and stromal tumours.PMID 28002623Read ↗

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