Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exosome-mediated miR-33 transfer induces M1 polarization in mouse macrophages and exerts antitumor effect in 4T1 breast cancer cell line.

International immunopharmacology - 1 Jan 2021

Moradi-Chaleshtori Maryam, Bandehpour Mojgan, Heidari Neda, Mohammadi-Yeganeh Samira, Mahmoud Hashemi Seyed

Abstract excerpt

Macrophages are the most abundant tumor-infiltrating immune cells. Macrophages are conventionally classified as M1 or M2 types. M2 type is the dominant phenotype of macrophages in the tumor microenvironment. M2 macrophages support different aspects of tumor development, including tumor formation, growth, and metastasis. MicroRNAs (miRNAs) have been demonstrated to regulate numerous cellular processes, including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytokines

Share to Exosomes

Share to Mice, Inbred BALB C

Share to MicroRNAs

Share to Neoplasm Invasiveness

Share to Tumor-Associated Macrophages

Source

Identifiers

PMID: 33249048
DOI: 10.1016/j.intimp.2020.107198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exosome-mediated miR-33 transfer induces M1 polarization in mouse macrophages and exerts antitumor effect in 4T1 breast cancer cell line.PMID 33249048Read ↗

In vitro and in vivo evaluation of anti-tumoral effect of M1 phenotype induction in macrophages by miR-130 and miR-33 containing exosomes.Semantic proximity Read ↗

Exosomes derived from rapamycin-treated 4T1 breast cancer cells induced polarization of macrophages to M1 phenotype.Semantic proximity Read ↗

Exosomal miRNAs-mediated macrophage polarization and its potential clinical application.Semantic proximity Read ↗

Tumor-derived exosomes in the regulation of macrophage polarization.Semantic proximity Read ↗

Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting.Semantic proximity Read ↗

[Influencing Factors and Significance of Tumor-associated Macrophage Polarization in Tumor Microenvironment].Semantic proximity Read ↗

Diffuse large B-cell lymphoma-derived exosomes push macrophage polarization toward M2 phenotype via GP130/STAT3 signaling pathway.Semantic proximity Read ↗

Phenotypic comparison and the potential antitumor function of immortalized bone marrow-derived macrophages (iBMDMs)Semantic proximity Read ↗

IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis.Semantic proximity Read ↗

Tumor-derived microparticles promoted M2-like macrophages polarization to stimulate osteosarcoma progression.Semantic proximity Read ↗

Generation of novel diagnostic and therapeutic exosomes to detect and deplete pro-tumorigenic M2-macrophagesSemantic proximity Read ↗

M1-like tumor-associated macrophages cascade a mesenchymal/stem-like phenotype of oral squamous cell carcinoma via the IL6/Stat3/THBS1 feedback loop.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.