Article
Tumor-derived exosomes in the regulation of macrophage polarization.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 May 2020
Baig Mirza S, Roy Anjali, Rajpoot Sajjan, Liu Dongfang, Savai Rajkumar, Banerjee Sreeparna, Kawada Manabu, Faisal Syed M, Saluja Rohit, Saqib Uzma, Ohishi Tomokazu, Wary Kishore K
Abstract excerpt
BACKGROUND: This review focuses on exosomes derived from various cancer cells. The review discusses the possibility of differentiating macrophages in alternatively activated anti-inflammatory pro-tumorigenic M2 macrophage phenotypes and classically activated pro-inflammatory, anti-tumorigenic M1 macrophage phenotypes in the tumor microenvironment (TME). The review is divided into two main parts, as follows: (1)...
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