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Article

Diffuse large B-cell lymphoma-derived exosomes push macrophage polarization toward M2 phenotype via GP130/STAT3 signaling pathway.

Chemico-biological interactions - 25 Jan 2022

Ling Hua Yu, Yang Zhong, Wang Pan Jun, Sun Yu, Ju Song Guang, Li Jun, Fu Jin Xiang

Abstract excerpt

Growing evidence shows that cancer progression links with both heterogeneity of the tumor microenvironment and dysregulated activity of immune cells. Cancer-secreted exosomes are being recognized as indispensable mediators of the exchange cargo between cancer and immune cells. The M2-phenotype tumor-associated macrophages have the function of promoting tumor progression and drug resistance. Diffuse large B-cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34922904
DOI: 10.1016/j.cbi.2021.109779

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