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Article

Tumor-derived microparticles promoted M2-like macrophages polarization to stimulate osteosarcoma progression.

The international journal of biochemistry & cell biology - 1 Jan 2024

Li Cui, Xiang Feifan, Gong Yuqi, Fu Yi, Chen Ge, Wang Zhi, Li Zhong, Wei Daiqing

Abstract excerpt

Microparticles (MPs) are a heterogeneous subpopulation of extracellular vesicles that originate from the plasma membranes of cells. There is increasing evidence that tumor-derived MPs (T-MPs) play a significant role in tumor progression and immune response in cancer. In our study, we found an increased secretion of MPs in osteosarcoma tissues obtained from metastatic patients. These T-MPs promoted polarization of...

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Identifiers

PMID: 37956954
DOI: 10.1016/j.biocel.2023.106494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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