Role of rs10406069 in miR-5196 in hyperdiploid childhood acute lymphoblastic leukemia.

doi:10.2217/epi-2020-0152

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Article

Role of rs10406069 in miR-5196 in hyperdiploid childhood acute lymphoblastic leukemia.

Epigenomics - 1 Nov 2020

Gutierrez-Camino Angela, Richer Chantal, St-Onge Pascal, Lopez-Lopez Elixabet, Bañeres Ana Carbone, de Andoin Nagore Garcia, Sastre Ana, Astigarraga Itziar, Martin-Guerrero Idoia, Sinnett Daniel, Garcia-Orad Africa

Abstract excerpt

Aim: To determine the role of single nucleotide polymorphisms (SNPs) in noncoding RNAs in childhood acute lymphoblastic leukemia (ALL) subtypes. Materials & methods: We screened all SNPs in 130 pre-miRNA genes to assess their role in the susceptibility of the most common subtypes of ALL: hyperdiploid and ETV6-RUNX1. Results: In two independent cohorts, we found a significant association between rs10406069 in...

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Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Core Binding Factor Alpha 2 Subunit

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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PMID: 33245684
DOI: 10.2217/epi-2020-0152

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