Article
A population-based single nucleotide polymorphism array analysis of genomic aberrations in younger adult acute lymphoblastic leukemia patients.
Genes, chromosomes & cancer - 1 May 2015
Dirse Vaidas, Bertasiute Agne, Gineikiene Egle, Zvirblis Tadas, Dambrauskiene Ruta, Gerbutavicius Rolandas, Juozaityte Elona, Malciute Ligita, Paulsson Kajsa, Griskevicius Laimonas
Abstract excerpt
Adult acute lymphoblastic leukemia (ALL) is characterized by a high frequency of abnormal karyotypes some of which are related to outcome. Single nucleotide polymorphism (SNP) array analysis provides a highly sensitive platform to detect large and small genomic aberrations. SNP array profiling data in adult ALL are limited and further systematic studies of this patient group are needed. We performed a...
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