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Article

Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

Proceedings of the National Academy of Sciences of the United States of America - 14 Dec 2010

Paulsson Kajsa, Forestier Erik, Lilljebjörn Henrik, Heldrup Jesper, Behrendtz Mikael, Young Bryan D, Johansson Bertil

Abstract excerpt

High hyperdiploid acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. It is characterized by gain of chromosomes, typically +X, +4, +6, +10, +14, +17, +18, and +21,+21; little is known about additional genetic aberrations. Approximately 20% of the patients relap...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Source

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Identifiers

PMID: 21098271
DOI: 10.1073/pnas.1006981107
PMCID: PMC3003126

Genes

PAN3
ETV6
PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21098271-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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