Article
Autosomal Clonal Monoallelic Expression: Natural or Artifactual?
Trends in genetics : TIG - 1 Mar 2021
Rv P, Sundaresh A, Karunyaa M, Arun A, Gayen S
Abstract excerpt
The prevalence of mitotically heritable clonal random monoallelic expression of autosomal genes (aRME) remains controversial. Specifically, presence of clonal aRME is well supported in vitro but remains elusive in vivo. Here, we provide critical insights into this matter and discuss whether prevalent clonal aRME is natural or artifactual.
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