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Mouse embryonic stem cell‐derived motor neurons are susceptible to ferroptosis

3 Jan 2023

Abstract excerpt

Ferroptosis is a regulated form of cell death driven by the lethal accumulation of lipid peroxides in cell membranes. Several regulators of ferroptosis have been identified using cancer cell lines. However, the cellular pathways of ferroptosis in neurons remain poorly characterized. In this study, we used a mouse embryonic stem cell‐derived motor neuron model to investigate how motor neurons respond to...

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PMID: 36595221
DOI: 10.1002/2211-5463.13545

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