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Article

SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients.

Diabetes - 1 Feb 2021

Fløyel Tina, Meyerovich Kira, Prause Michala C, Kaur Simranjeet, Frørup Caroline, Mortensen Henrik B, Nielsen Lotte B, Pociot Flemming, Cardozo Alessandra K, Størling Joachim

Abstract excerpt

The single nucleotide polymorphism rs7804356 located in the Src kinase-associated phosphoprotein 2 (SKAP2) gene is associated with type 1 diabetes (T1D), suggesting SKAP2 as a causal candidate gene. The objective of the study was to investigate if SKAP2 has a functional role in the β-cells in relation to T1D. In a cohort of children with newly diagnosed T1D, rs7804356 predicted glycemic control and residual...

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Source

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Identifiers

PMID: 33203694
DOI: 10.2337/db20-0092
PMCID: PMC7881866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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