Inflammatory signaling pathways in pancreatic β-cell: New insights into type 2 diabetes pathogenesis

Abstract excerpt

Type 2 diabetes (T2D) is a complex metabolic disorder with a growing global prevalence, and there is a linking between inflammation in pancreatic β-cell and impaired glucose homeostasis which has emerged as a key player in the pathogenesis of T2D. Recent advances in research have provided new insights into various inflammatory signaling cascades in β-cell among which we focus on Toll-like Receptor 4 (TLR4),...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diabetes and associated disorders
• Share to Pancreatic function and diabetes
• Share to Pancreatitis Pathology and Treatment