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Article

Genetic Association in the HLA Region.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Moutsianas Loukas, Gutierrez-Achury Javier

Abstract excerpt

The MHC/HLA region has been consistently associated with a large number of complex traits, including but not limited to, most immune-mediated ones. Efforts to pinpoint drivers of this commonly encountered association peak at the short arm of chromosome 6, however, have been challenging, owing to the high density of genes and the long and extended linkage disequilibrium that are characteristic of this region.The...

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PMID: 29876894
DOI: 10.1007/978-1-4939-7868-7_8

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