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Article

Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3+ CD8+ T Cells and Survival in Diffuse Large B Cell Lymphoma.

Journal of immunology research - 1 Jan 2020

Zhang Tingting, Ren Tianyuan, Song Zheng, Zhao Jing, Jiao Lei, Zhang Zhenzhen, He Jin, Liu Xianming, Qiu Lihua, Li Lanfang, Zhou Shiyong, Meng Bin, Zhai Qiongli, Ren Xiubao, Qian Zhengzi, Wang Xianhuo, Zhang Huilai

Abstract excerpt

Tim-3 is a promising target for antitumor immunotherapy. A number of clinical trials are evaluating the efficacy of anti-Tim-3 therapies as a single agent or combinations in solid tumors and haematologic malignancies. However, there remains a considerable lack of data on Tim-3 signalling, especially the genetic characteristics and immune microenvironment, in diffuse large B cell lymphoma (DLBCL). Herein, we...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis A Virus Cellular Receptor 2

Share to High-Throughput Nucleotide Sequencing

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Source

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Identifiers

PMID: 33178839
DOI: 10.1155/2020/6968595
PMCID: PMC7647777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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