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Immune regulation by Tim-3

14 Mar 2018

Abstract excerpt

T-cell immunoglobulin and mucin domain 3 (Tim-3) is a transmembrane protein that in both mice and humans has been shown to possess various functions in a context-dependent manner. Thus, Tim-3 has been associated with both inhibitory and co-stimulatory function, depending in part on the specific cell type and immune response course. Though originally described on T cells, Tim-3 is now known to be expressed by both...

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Identifiers

PMID: 29560265
DOI: 10.12688/f1000research.13446.1

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