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Emerging Insights into TIM-3: A Potential Immune Checkpoint for Lung Cancer Immunotherapeutic Strategies.

Immunological investigations - 1 Jan 2026

B Allela Omer Qutaiba, Shareef Abdulkareem, Kumar Bishoyi Ashok, Oweis Rami, Ballal Suhas, Singh Abhayveer, Sinha Aashna, Ray Subhashree, Sameer Hayder Naji, Yaseen Ahmed, Athab Zainab H, Adil Mohaned

Abstract excerpt

BACKGROUND: Recent advancements in cancer therapy have focused on blocking immune checkpoint receptors (ICRs) to restore anti-tumor immunity. Despite these developments, a significant proportion of patients remain unresponsive to currently available immune checkpoint inhibitors (ICIs), highlighting the urgent need for novel therapeutic targets. T-cell immunoglobulin mucin-3 (TIM-3) has emerged as a new immune...

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PMID: 41143621
DOI: 10.1080/08820139.2025.2571960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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