Article
Assessment of Imputation from Low-Pass Sequencing to Predict Merit of Beef Steers.
Genes - 5 Nov 2020
Snelling Warren M, Hoff Jesse L, Li Jeremiah H, Kuehn Larry A, Keel Brittney N, Lindholm-Perry Amanda K, Pickrell Joseph K
Abstract excerpt
Decreasing costs are making low coverage sequencing with imputation to a comprehensive reference panel an attractive alternative to obtain functional variant genotypes that can increase the accuracy of genomic prediction. To assess the potential of low-pass sequencing, genomic sequence of 77 steers sequenced to >10X coverage was downsampled to 1X and imputed to a reference of 946 cattle representing multiple Bos...
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