Article
Accuracy of imputation to whole-genome sequence data in Holstein Friesian cattle.
Genetics, selection, evolution : GSE - 15 Jul 2014
van Binsbergen Rianne, Bink Marco Cam, Calus Mario Pl, van Eeuwijk Fred A, Hayes Ben J, Hulsegge Ina, Veerkamp Roel F
Abstract excerpt
BACKGROUND: The use of whole-genome sequence data can lead to higher accuracy in genome-wide association studies and genomic predictions. However, to benefit from whole-genome sequence data, a large dataset of sequenced individuals is needed. Imputation from SNP panels, such as the Illumina BovineSNP50 BeadChip and Illumina BovineHD BeadChip, to whole-genome sequence data is an attractive and less expensive...
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