Article
Imputation of high-density genotypes in the Fleckvieh cattle population.
Genetics, selection, evolution : GSE - 13 Feb 2013
Pausch Hubert, Aigner Bernhard, Emmerling Reiner, Edel Christian, Götz Kay-Uwe, Fries Ruedi
Abstract excerpt
BACKGROUND: Currently, genome-wide evaluation of cattle populations is based on SNP-genotyping using ~ 54,000 SNP. Increasing the number of markers might improve genomic predictions and power of genome-wide association studies. Imputation of genotypes makes it possible to extrapolate genotypes from lower to higher density arrays based on a representative reference sample for which genotypes are obtained at higher...
Topics
- Algorithms
- Animals
- Animals, Inbred Strains
- Cattle
- Data Interpretation, Statistical
- Genotype
- Genotyping Techniques
- Male
- Pedigree
- Polymorphism, Single Nucleotide
- Population