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Article

Retinoic acid increases phagocytosis of myelin by macrophages.

Journal of cellular physiology - 1 May 2021

Wu Siyu, Romero-Ramírez Lorenzo, Mey Jörg

Abstract excerpt

Traumatic injuries of the central nervous system (CNS) are followed by the accumulation of cellular debris including proteins and lipids from myelinated fiber tracts. Insufficient phagocytic clearance of myelin debris influences the pathological process because it induces inflammation and blocks axonal regeneration. We investigated whether ligands of nuclear receptor families retinoic acid receptors (RARs),...

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Share to Macrophages
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phagocytosis

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Share to Receptors, Cytoplasmic and Nuclear

Share to Receptors, Retinoic Acid

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Source

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Identifiers

PMID: 33165955
DOI: 10.1002/jcp.30137
PMCID: PMC7984038

Genes

CD36
TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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