Article
Classically and alternatively activated bone marrow derived macrophages differ in cytoskeletal functions and migration towards specific CNS cell types.
Journal of neuroinflammation - 26 May 2011
Vereyken Elly J F, Heijnen Priscilla D A M, Baron Wia, de Vries Elga H E, Dijkstra Christine D, Teunissen Charlotte E
Abstract excerpt
BACKGROUND: Macrophages play an important role in neuroinflammatory diseases such as multiple sclerosis (MS) and spinal cord injury (SCI), being involved in both damage and repair. The divergent effects of macrophages might be explained by their different activation status: classically activated (CA/M1), pro-inflammatory, macrophages and alternatively activated (AA/M2), growth promoting, macrophages. Little is...
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