Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination.

doi:10.1016/0165-5728(92)90129-9

Back to search

Article

Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination.

Journal of neuroimmunology - 1 Oct 1992

Griffin J W, George R, Lobato C, Tyor W R, Yan L C, Glass J D

Abstract excerpt

Macrophages are important effector cells in immune-mediated demyelination. Current concepts regarding their entry and activation focus on the effects of T-cell-derived cytokines. This presentation describes the responses of macrophages and microglia to a non-inflammatory, non-immune injury, Walle...

Topics

Animals
Demyelinating Diseases
Humans
Macrophages
Myelin Sheath
Nervous System
Nervous System Physiological Phenomena
Phenotype
Reference Values
Wallerian Degeneration

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.