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Article

Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination.

Journal of neuroimmunology - 1 Oct 1992

Griffin J W, George R, Lobato C, Tyor W R, Yan L C, Glass J D

Abstract excerpt

Macrophages are important effector cells in immune-mediated demyelination. Current concepts regarding their entry and activation focus on the effects of T-cell-derived cytokines. This presentation describes the responses of macrophages and microglia to a non-inflammatory, non-immune injury, Wallerian degeneration. During Wallerian degeneration in the peripheral nervous system (PNS), macrophages are promptly and...

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Identifiers

PMID: 1430148
DOI: 10.1016/0165-5728(92)90129-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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