Genetic lesions in preleukemia.

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Article

Genetic lesions in preleukemia.

Critical reviews in oncogenesis - 1 Jan 1992

Carter G, Ridge S, Padua R A

Abstract excerpt

Preleukemia is thought to be a clonal disorder of hemopoietic stem cells. The conversion of a normal cell into a preleukemic and ultimately leukemic state is a multistep process requiring the accumulation of a number of genetic lesions. The myelodysplastic syndromes have become a paradigm for hum...

Topics

Chromosome Aberrations
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 7
Chromosomes, Human, Pair 8
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Genes, ras
Humans
Leukemia, Myeloid, Acute
Macrophage Colony-Stimulating Factor
Mutation
Myelodysplastic Syndromes
Preleukemia
Proto-Oncogene Mas

Source

Open in PubMed

Identifiers

PMID: 1420444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1420444-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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