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Article

Targeted Genomic Sequencing Reveals Different Evolutionary Patterns Between Locally and Distally Recurrent Glioblastomas.

Cancer genomics & proteomics - 1 Jan 2000

Yoon Nara, Kim Hyun-Soo, Lee Jung Whee, Lee Eui-Jin, Maeng Lee-So, Yoon Wan Soo

Abstract excerpt

BACKGROUND/AIM: Glioblastoma is the most malignant form of astrocytoma. The purpose of this study was to analyze the genetic characteristics of primary and recurrent glioblastomas using targeted sequencing and investigate the differences in mutational profiles between the locations of tumor recurrence. MATERIALS AND METHODS: Fourteen glioblastoma patients who developed local (n=10) or distal (n=4) recurrence were...

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Biomarkers, Tumor
Brain Neoplasms
Evolution, Molecular
Gene Expression Regulation, Neoplastic
Glioblastoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

High-Throughput Nucleotide Sequencing

Neoplasm Recurrence, Local

Whole Genome Sequencing

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Identifiers

PMID: 33099481
DOI: 10.21873/cgp.20234
PMCID: PMC7675659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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