Article
From astrocytoma to glioblastoma: a clonal evolution study.
FEBS open bio - 1 May 2020
Yang Fuhua, Zou Yunding, Gong Qiang, Chen Jieping, Li Wei-Dong, Huang Qilin
Abstract excerpt
Astrocytomas often recur after surgical resection, but the underlying mechanism remains enigmatic. Elucidation of clonal evolution in primary and relapse tumors may provide important information on tumor progression. Here, we examined genetic factors underlying recurrence in a patient with astrocytoma initially diagnosed with World Health Organization (WHO) grade II astrocytoma, who then relapsed with...
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