Article
Molecular and clonal evolution in recurrent metastatic gliosarcoma.
Cold Spring Harbor molecular case studies - 1 Feb 2020
Anderson Kevin J, Tan Aaron C, Parkinson Jonathon, Back Michael, Kastelan Marina, Newey Allison, Brewer Janice, Wheeler Helen, Hudson Amanda L, Amin Samirkumar B, Johnson Kevin C, Barthel Floris P, Verhaak Roel G W, Khasraw Mustafa
Abstract excerpt
We discuss the molecular evolution of gliosarcoma, a mesenchymal type of glioblastoma (GBM), using the case of a 37-yr-old woman who developed two recurrences and an extracranial metastasis. She was initially diagnosed with isocitrate dehydrogenase (IDH) wild-type gliosarcoma in the frontal lobe and treated with surgery followed by concurrent radiotherapy with temozolomide. Five months later the tumor recurred in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.