Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distant origin of glioblastoma recurrence: neural stem cells in the subventricular zone serve as a source of tumor reconstruction after primary resection

3 Mar 2025

Abstract excerpt

Glioblastoma (GBM) is the most aggressive and common type of primary malignant brain cancer in adults. GBM often recurs locally near the resection cavity (RC) following the surgical removal of primary tumors. Recent research has reported that neural stem cells (NSCs) in the subventricular zone (SVZ) harboring cancer-driving mutations serve as the cells of origin for human GBM. However, the pathological role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Glioma Diagnosis and Treatment
Share to Neurogenesis and neuroplasticity mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40033380
DOI: 10.1186/s12943-025-02273-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distant origin of glioblastoma recurrence: neural stem cells in the subventricular zone serve as a source of tumor reconstruction after primary resectionPMID 40033380Read ↗

The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and ModelingSemantic proximity Read ↗

Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cellsSemantic proximity Read ↗

Essential Gene Pathways for Glioblastoma Stem Cells: Clinical Implications for Prevention of Tumor RecurrenceSemantic proximity Read ↗

Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent TumorSemantic proximity Read ↗

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution.Semantic proximity Read ↗

Neural Stem Cells as Potential Glioblastoma Cells of OriginSemantic proximity Read ↗

Human glioblastoma arises from subventricular zone cells with low-level driver mutations.Semantic proximity Read ↗

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent GliomaSemantic proximity Read ↗

Overcoming therapeutic resistance in glioblastoma: the way forwardSemantic proximity Read ↗

Targeted Genomic Sequencing Reveals Different Evolutionary Patterns Between Locally and Distally Recurrent Glioblastomas.Semantic proximity Read ↗

Genetic Architectures and Cell-of-Origin in GlioblastomaSemantic proximity Read ↗

Hitting a Moving Target: Glioma Stem Cells Demand New Approaches in Glioblastoma TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.