Article
Genetic characterization of an aggressive optic nerve pilocytic glioma.
Brain tumor pathology - 1 Jan 2021
Hong Christopher S, Fliney Greg, Fisayo Adeniyi, An Yi, Gopal Pallavi P, Omuro Antonio, Pointdujour-Lim Renelle, Erson-Omay E Zeynep, Omay S Bulent
Abstract excerpt
Optic nerve glioma (ONG) is a rare, typically slow-growing WHO I grade tumor that affects the visual pathways. ONG is most commonly seen in the pediatric population, in association with neurofibromatosis type 1 syndrome. However, sporadic adult cases may also occur and may clinically behave more aggressively, despite benign histopathology. Genetic characterization of these tumors, particularly in the adult...
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