Article
Optic nerve sheath meningiomas harbor distinct genetic variants.
American journal of clinical pathology - 5 Jan 2026
Hulbert Samuel W, Lopez Gianluca, Chen Liam, Chen Suping, Pallavajjala Aparna, Haley Lisa, Nelson Aaron J Z, Maniar Arpita, Kazim Michael, Sullivan Timothy, Eberhart Charles G, Rodriguez Fausto J, Miller Neil R
Abstract excerpt
OBJECTIVE: Both primary optic nerve sheath meningiomas (pONSMs) and secondary optic nerve sheath meningiomas (sONSMs) pose clinical challenges because standard treatments such as surgical debulking and radiation therapy can further damage the optic nerve, producing permanent visual loss. The molecular pathology of primary skull base meningiomas is becoming clearer. However, by comparison, pONSMs and sONSMs have...
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