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Article

IDH clonal heterogeneity segregates a subgroup of non-1p/19q codeleted gliomas with unfavourable clinical outcome.

Neuropathology and applied neurobiology - 1 Apr 2021

Luo Shangyi, Zhu Shiwei, Liao Jianlong, Zhang Yajing, Hou Xiaobo, Luo Tao, Zhao Erjie, Xu Jinyuan, Pang Lin, Liang Xin, Xiao Yun, Li Xia

Abstract excerpt

AIMS: Diffuse gliomas (DGs) are classified into three major molecular subgroups following the revised World Health Organisation (WHO) classification criteria based on their IDH mutation and 1p/19q codeletion status. However, substantial biological heterogeneity and differences in the clinical course are apparent within each subgroup, which remain to be resolved. We sought to assess the clonal status of somatic...

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PMID: 33098109
DOI: 10.1111/nan.12671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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