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Article

Association of IDH mutation and 1p19q co-deletion with tumor immune microenvironment in lower-grade glioma

28 Apr 2021

Abstract excerpt

Although the successful clinical trials of immunotherapy show promising strategies for many cancers, its application in glioma has lagged in comparison with the progress seen in other cancers. Both isocitrate dehydrogenase (IDH) mutations and 1p/19q codeletions are critical molecular alterations affecting therapeutic response in lower-grade glioma (LGG). The systematic and comprehensive characterization of the...

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PMID: 34141867
DOI: 10.1016/j.omto.2021.04.010

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