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Article

A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank.

PLoS genetics - 1 Oct 2020

Qian Junyang, Tanigawa Yosuke, Du Wenfei, Aguirre Matthew, Chang Chris, Tibshirani Robert, Rivas Manuel A, Hastie Trevor

Abstract excerpt

The UK Biobank is a very large, prospective population-based cohort study across the United Kingdom. It provides unprecedented opportunities for researchers to investigate the relationship between genotypic information and phenotypes of interest. Multiple regression methods, compared with genome-wide association studies (GWAS), have already been showed to greatly improve the prediction performance for a variety...

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PMID: 33095761
DOI: 10.1371/journal.pgen.1009141
PMCID: PMC7641476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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