Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KinFams: De-Novo Classification of Protein Kinases Using CATH Functional Units

2 Feb 2023

Abstract excerpt

Protein kinases are important targets for treating human disorders, and they are the second most targeted families after G-protein coupled receptors. Several resources provide classification of kinases into evolutionary families (based on sequence homology); however, very few systematically classify functional families (FunFams) comprising evolutionary relatives that share similar functional properties. We have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioinformatics and Genomic Networks
Share to Computational Drug Discovery Methods
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36830646
DOI: 10.3390/biom13020277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KinFams: De-Novo Classification of Protein Kinases Using CATH Functional UnitsPMID 36830646Read ↗

Novel universal domain-centric method for protein classificationSemantic proximity Read ↗

A resource for exploring the understudied human kinome for research and therapeutic opportunitiesSemantic proximity Read ↗

KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinasesSemantic proximity Read ↗

Deep Learning enabled discovery of kinase drug targets in PharosSemantic proximity Read ↗

KinView: a visual comparative sequence analysis tool for integrated kinome research.Semantic proximity Read ↗

KinaseMD: kinase mutations and drug response database.Semantic proximity Read ↗

Progress Towards a Public Chemogenomic Set for Protein Kinases and a Call for ContributionsSemantic proximity Read ↗

K-Map: connecting kinases with therapeutics for drug repurposing and development.Semantic proximity Read ↗

Kinase Interaction Network Expands Functional and Disease Roles of Human KinasesSemantic proximity Read ↗

KinMutBase, a database of human disease-causing protein kinase mutations.Semantic proximity Read ↗

Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and structural diversity.Semantic proximity Read ↗

The Clinical Kinase Index: A Method to Prioritize Understudied Kinases as Drug Targets for the Treatment of Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.