Article
KinaseMD: kinase mutations and drug response database.
Nucleic acids research - 8 Jan 2021
Hu Ruifeng, Xu Haodong, Jia Peilin, Zhao Zhongming
Abstract excerpt
Mutations in kinases are abundant and critical to study signaling pathways and regulatory roles in human disease, especially in cancer. Somatic mutations in kinase genes can affect drug treatment, both sensitivity and resistance, to clinically used kinase inhibitors. Here, we present a newly constructed database, KinaseMD (kinase mutations and drug response), to structurally and functionally annotate kinase...
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