Article

Phylomedicine of mutational processes in somatic cancer cell populations

2021-04-04

Abstract excerpt

<h4>ABSTRACT</h4> Mutational processes in somatic cancer cell populations are constantly changing, leaving their signatures in the accumulated genomic variation in tumors. The inference of mutational signatures from the observed genetic variation enables spatiotemporal tracking of tumor mutational processes that evolve due to cellular environmental changes, mutations, and treatment regimes. Ultimately, mutational...

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Literature Corpus work: 1d5b7055-96a8-546c-a9da-28cbdb9bae67
DOI: 10.1101/2021.04.02.438268

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