Article
Do myeloproliferative neoplasms and multiple myeloma share the same genetic susceptibility loci?
International journal of cancer - 1 Apr 2021
Macauda Angelica, Giaccherini Matteo, Sainz Juan, Gemignani Federica, Sgherza Nicola, Sánchez-Maldonado José Manuel, Gora-Tybor Joanna, Martinez-Lopez Joaquin, Carreño-Tarragona Gonzalo, Jerez Andrés, Spadano Raffaele, Gołos Aleksandra, Jurado Manuel, Hernández-Mohedo Francisca, Mazur Grzegorz, Tavano Francesca, Butrym Aleksandra, Várkonyi Judit, Canzian Federico, Campa Daniele
Abstract excerpt
Myeloproliferative neoplasms (MPNs) are a group of diseases that cause myeloid hematopoietic cells to overproliferate. Epidemiological and familial studies suggest that genetic factors contribute to the risk of developing MPN, but the genetic susceptibility of MPN is still not well known. Indeed, only few loci are known to have a clear role in the predisposition to this disease. Some studies reported a diagnosis...
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