Article
Genetic characterization of the ALFA study: Uncovering genetic profiles in the Alzheimer's continuum.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Mar 2024
Vilor-Tejedor Natalia, Genius Patricia, Rodríguez-Fernández Blanca, Minguillón Carolina, Sadeghi Iman, González-Escalante Armand, Crous-Bou Marta, Suárez-Calvet Marc, Grau-Rivera Oriol, Brugulat-Serrat Anna, Sánchez-Benavides Gonzalo, Esteller Manel, Fauria Karine, Molinuevo José Luis, Navarro Arcadi, Gispert Juan Domingo
Abstract excerpt
INTRODUCTION: In 2013, the ALzheimer's and FAmilies (ALFA) project was established to investigate pathophysiological changes in preclinical Alzheimer's disease (AD), and to foster research on early detection and preventive interventions. METHODS: We conducted a comprehensive genetic characterization of ALFA participants with respect to neurodegenerative/cerebrovascular diseases, AD biomarkers, brain...
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