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Article

Landscape of Genome-Wide DNA Methylation of Colorectal Cancer Metastasis

22 Sept 2020

Abstract excerpt

Colorectal cancer is a heterogeneous disease caused by both genetic and epigenetics factors. Analysing DNA methylation changes occurring during colorectal cancer progression and metastasis formation is crucial for the identification of novel epigenetic markers of patient prognosis. Genome-wide methylation sequencing of paired samples of colon (normal adjacent, primary tumour and lymph node metastasis) showed...

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PMID: 32971738
DOI: 10.3390/cancers12092710

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