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Exome scale map of genetic alterations promoting metastasis in colorectal cancer

19 Sept 2018

Abstract excerpt

BACKGROUND: Approximately 90% of colorectal cancer (CRC) deaths are caused by tumors ability to migrate into the adjacent tissues and metastase into distant organs. More than 40 genes have been causally linked to the development of CRC but no mutations have been associated with metastasis yet. To identify molecular basis of CRC metastasis we performed whole-exome and genome-scale transcriptome sequencing of 7...

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Share to Colorectal Cancer Treatments and Studies
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PMID: 30231850
DOI: 10.1186/s12863-018-0673-0

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