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Article

Candida albicans Double Mutants Lacking both EFG1 and WOR1 Can Still Switch to Opaque.

mSphere - 23 Sept 2020

Park Yang-Nim, Pujol Claude, Wessels Deborah J, Soll David R

Abstract excerpt

Candida albicans, a pervasive opportunistic pathogen, undergoes a unique phenotypic transition from a "white" phenotype to an "opaque" phenotype. The switch to opaque impacts gene expression, cell morphology, wall structure, metabolism, biofilm formation, mating, virulence, and colonization of the skin and gastrointestinal (GI) tract. Although the regulation of switching is complex, a paradigm has evolved from a...

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Identifiers

PMID: 32968010
DOI: 10.1128/mSphere.00918-20
PMCID: PMC7568642

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Candida albicans Double Mutants Lacking both EFG1 and WOR1 Can Still Switch to Opaque.PMID 32968010Read ↗

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