Article
Discovery of a "white-gray-opaque" tristable phenotypic switching system in candida albicans: roles of non-genetic diversity in host adaptation.
PLoS biology - 1 Apr 2014
Tao Li, Du Han, Guan Guobo, Dai Yu, Nobile Clarissa J, Liang Weihong, Cao Chengjun, Zhang Qiuyu, Zhong Jin, Huang Guanghua
Abstract excerpt
Non-genetic phenotypic variations play a critical role in the adaption to environmental changes in microbial organisms. Candida albicans, a major human fungal pathogen, can switch between several morphological phenotypes. This ability is critical for its commensal lifestyle and for its ability to cause infections. Here, we report the discovery of a novel morphological form in C. albicans, referred to as the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
