Article
Negative control of Candida albicans biofilm formation by combined action of white-opaque regulator Wor2 and biofilm regulator Bcr1.
G3 (Bethesda, Md.) - 6 Jul 2026
Goerlich Katharina, Mitchell Aaron P
Abstract excerpt
Biofilm formation is vital for the survival and pathogenicity of the fungus Candida albicans. Expression of biofilm-promoting genes is coordinated by a transcription factor network that governs the yeast-filament transition and other processes. A second cell type transition, the white-opaque transition, is coordinated by its own transcription factor network. Initial studies suggested that the 2 transcriptional...
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